Bismuth Subsalicylate
Bismuth Subsalicylate is the most commonly used API to manufacture OTC drugs that are the gold standard in the treatment of diarrhea.
Other uses:
Given its bacteriostatic properties Bismuth Subsalicylate is also used widely in the treatment to erradicate H-pylori
Specifications
Generic name: | Bismuth Subsalicylate | Primary packaging | Polyethylene bag |
|---|---|---|---|
Molecular formula | C7H5BiO4 | Secondary packaging | Cardboard fiber drum |
Molecular weight | 362.09 g/mol. | Internal product code | PTQ-4.6.2 |
Presentation | White powder | Retest date: | 48 months |
Storage conditions | Environment, protect from direct sunlight exposure | CAS Number: | 14882-18-9 |
TEST | SPECIFICATION |
|---|---|
Appearance | White powder |
Solubility | Practically insoluble in water and in alcohol. It dissolves in mineral acids with decomposition. |
Identification | Positive for Bi+3 |
% Loss on drying | ≤ 1.00% |
% Assay (As Bi+3) | 56.00-59.40 |
% Assay (As Bi2O3) | 62.40-66.20 |
pH | 2.7-5.0 |
% Acidity | ≤ 0.25% |
% Free salicylic acid | ≤ 0.0020% |
% Total salicylates | 36.50-39.30% |
% Arsenic | ≤ 0.0010% |
% Copper | ≤ 0.0010% |
% Lead | ≤ 0.0010% |
% Silver | ≤ 0.0010% |
% Chlorides | ≤ 0.020% |
% Nitrates | ≤ 0.40% |
% Soluble bismuth | ≤ 0.0040% |
